Whole-genome sequencing of Aspergillus tubingensis G131 and overview of its secondary metabolism potential.

ABSTRACT:

Background

Black Aspergilli represent one of the most important fungal resources of primary and secondary metabolites for biotechnological industry. Having several black Aspergilli sequenced genomes should allow targeting the production of certain metabolites with bioactive properties.

Results

In this study, we report the draft genome of a black Aspergilli, A. tubingensis G131, isolated from a French Mediterranean vineyard. This 35 Mb genome includes 10,994 predicted genes. A genomic-based discovery identifies 80 secondary metabolites biosynthetic gene clusters. Genomic sequences of these clusters were blasted on 3 chosen black Aspergilli genomes: A. tubingensis CBS 134.48, A. niger CBS 513.88 and A. kawachii IFO 4308. This comparison highlights different levels of clusters

SUBMITTER: Choque E 

PROVIDER: S-EPMC6389250 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature