Influence of fluoride on the mineralization of collagen via the polymer-induced liquid-precursor (PILP) process.

ABSTRACT:

Objective

The polymer-induced liquid-precursor (PILP) mineralization process has been shown to remineralize artificial dentin lesions to levels consistent with those of native dentin. However, nanoindentation revealed that the moduli of those remineralized lesions were only ∼50% that of native dentin. We hypothesize that this may be due to the PILP process having been previously optimized to obtain high amounts (∼70wt%) of intrafibrillar crystals, but without sufficient interfibrillar mineral, another significant component of dentin.

Methods

Fluoride was added to the PILP-mineralization of collagen from rat tail tendon at varying concentrations to determine if a better balance of intra- versus inter-fibrillar mineralization could be obtained, as determined by electron micros

SUBMITTER: Saxena N 

PROVIDER: S-EPMC6389359 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature