Noninvasive Prenatal Whole Genome Sequencing: Pregnant Women's Views and Preferences.

ABSTRACT:

Objective

To assess pregnant women's views and preferences on noninvasive prenatal whole genome sequencing.

Methods

A survey was offered to 805 pregnant women receiving prenatal care in practices affiliated with a large, tertiary care maternity hospital. Respondents were asked to envision undergoing prenatal whole genome sequencing and discuss their preferences and reasons for receiving different categories of genomic results, organized by actionability, severity, prevalence, and age of onset. The survey also queried respondents on their preferred role for clinicians in prenatal whole genome sequencing decision-making, and on their demographics and genetic literacy.

Results

From June to August 2017, a total of 553 respondents returned the survey (response rate=68.7%).

SUBMITTER: Sullivan HK 

PROVIDER: S-EPMC6389368 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature