Serum FABP4 concentrations decrease after Roux-en-Y gastric bypass but not after intensive medical management.

ABSTRACT:

Background

Serum concentrations of fatty acid binding protein 4, an adipose tissue fatty acid chaperone, have been correlated with insulin resistance and cardiovascular risk factors. The objective of this study were to assess relationships among Roux-en-Y gastric bypass, intensive lifestyle modification and medical management protocol, fatty acid binding protein 4, and metabolic parameters in obese patients with severe type 2 diabetes mellitus; and to evaluate the relative contribution of abdominal subcutaneous adipose and visceral adipose to the secretion of fatty acid binding protein 4.

Methods

Participants were randomly assigned to intensive lifestyle modification and medical management protocol (n = 29) or to intensive lifestyle modification and medical management protoc

SUBMITTER: Jahansouz C 

PROVIDER: S-EPMC6389424 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature