Developing BIOTEL: A Semi-Automated Spreadsheet for Estimating Telomere Length and Biological Age.

ABSTRACT: Introduction: Telomere length (TL) is causally related to aging and several age-related diseases. Specifically, the abundance of short telomeres and the rate of telomere shortening are strong determinants of cell homeostasis. Thus, tools for analyzing and manipulating TL data can vastly improve research focused on aging. Aim: In this study, we developed a semi-automated worksheet, BIOTEL, to generate individual and group TL statistics and provide a crude estimation of biological age. Results: Data from the Telomere Length Database Project (TLDP) were implemented to the spreadsheet to produce TL statistics. 150 participants were included, and their age was from 21 to 82 years, and the sex distribution ratio was 52.3%: 47.7% (male: female). Initially, we analyzed the fluorescen

SUBMITTER: Tsatsakis A 

PROVIDER: S-EPMC6389611 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature