Common and Specific Functional Activity Features in Schizophrenia, Major Depressive Disorder, and Bipolar Disorder.

ABSTRACT: Objectives: Schizophrenia (SZ), major depressive disorder (MDD), and bipolar disorder (BD) are serious mental disorders with distinct diagnostic criteria. They share common clinical and biological features. However, there are still only few studies on the common and specific brain imaging changes associated with the three mental disorders. Therefore, the aim of this study was to identify the common and specific functional activity and connectivity changes in SZ, MDD, and BD. Methods: A total of 271 individuals underwent functional magnetic resonance imaging: SZ (n = 64), MDD (n = 73), BD (n = 41), and healthy controls (n = 93). The symptoms of SZ patients were evaluated by the Positive and Negative Syndrome Scale. The Beck Depression Inventory (BDI

SUBMITTER: Yang Y 

PROVIDER: S-EPMC6389674 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature