Slower alpha rhythm associates with poorer seizure control in epilepsy.

ABSTRACT:

Objective

Slowing and frontal spread of the alpha rhythm have been reported in multiple epilepsy syndromes. We investigated whether these phenomena are associated with seizure control.

Methods

We prospectively acquired resting-state electroencephalogram (EEG) in 63 patients with focal and idiopathic generalized epilepsy (FE and IGE) and 39 age- and gender-matched healthy subjects (HS). Patients were divided into good and poor (≥4 seizures/12 months) seizure control groups based on self-reports and clinical records. We computed spectral power from 20-sec EEG segments during eyes-closed wakefulness, free of interictal abnormalities, and quantified power in high- and low-alpha bands. Analysis of covariance and post hoc t-tests were used to assess group differences in alp

SUBMITTER: Abela E 

PROVIDER: S-EPMC6389754 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature