Complete spermatogenesis in intratesticular testis tissue xenotransplants from immature non-human primate.
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ABSTRACT:
SUBMITTER: Ntemou E
PROVIDER: S-EPMC6389866 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Publications
Complete spermatogenesis in intratesticular testis tissue xenotransplants from immature non-human primate.
Ntemou E E Kadam P P Van Saen D D Wistuba J J Mitchell R T RT Schlatt S S Goossens E E
Human reproduction (Oxford, England) 20190301 3
<h4>Study question</h4>Can full spermatogenesis be achieved after xenotransplantation of prepubertal primate testis tissue to the mouse, in testis or subcutaneously?<h4>Summary answer</h4>Intratesticular xenotransplantation supported the differentiation of immature germ cells from marmoset (Callithrix jacchus) into spermatids and spermatozoa at 4 and 9 months post-transplantation, while in subcutaneous transplants, spermatogenic arrest was observed at 4 months and none of the transplants survive ...[more]
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