The prediction of suicide in severe mental illness: development and validation of a clinical prediction rule (OxMIS).

ABSTRACT: Assessment of suicide risk in individuals with severe mental illness is currently inconsistent, and based on clinical decision-making with or without tools developed for other purposes. We aimed to develop and validate a predictive model for suicide using data from linked population-based registers in individuals with severe mental illness. A national cohort of 75,158 Swedish individuals aged 15-65 with a diagnosis of severe mental illness (schizophrenia-spectrum disorders, and bipolar disorder) with 574,018 clinical patient episodes between 2001 and 2008, split into development (58,771 patients, 494 suicides) and external validation (16,387 patients, 139 suicides) samples. A multivariable derivation model was developed to determine the strength of pre-specified routinely collected socio-d

SUBMITTER: Fazel S 

PROVIDER: S-EPMC6389890 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature