Time-Dependent Toxicities of Quorum Sensing Inhibitors to Aliivibrio fischeri and Bacillus subtilis.

ABSTRACT: Quorum sensing inhibitors (QSIs) are being used widely as a promising alternative to antibiotics and drawing attention as potential pollutants. However, the assessment methods of the toxicities of QSIs, including model organism and affecting time, have not been established. To investigate how model organism and acting time impact the toxicities of QSIs, the effect of 4 QSIs to Aliivibrio fischeri and Bacillus subtilis were determined at different exposing time in the present study. The results showed that the toxic effects of QSIs to gram-negative bacteria (A fischeri) and gram-positive bacteria (B subtilis) were different and time dependent. As for A fischeri, QSI (furaneol acetate, FA) merely showed inhibition on the bioluminescence from hours 1 to 2. But from hours 3 to 6, low concentra

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC6390225 | biostudies-literature | 2019 Jan-Mar

REPOSITORIES: biostudies-literature