Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion.

ABSTRACT: Aging is a physiological process characterized by a progressive decline of biological functions and an increase in destructive processes in cells and organs. Physical activity and exercise positively affects the expression of skeletal muscle markers involved in longevity pathways. Recently, a new mechanism, autophagy, was introduced to the adaptations induced by acute and chronic exercise as responsible of positive metabolic modification and health-longevity promotion. However, the molecular mechanisms regulating autophagy in response to physical activity and exercise are sparsely described. We investigated the long-term adaptations resulting from lifelong recreational football training on the expression of skeletal muscle markers involved in autophagy signaling. We demonstrated that lifel

SUBMITTER: Mancini A 

PROVIDER: S-EPMC6390296 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature