Breastfeeding and vitamin D supplementation reduce the risk of Kawasaki disease in a German population-based case-control study.

ABSTRACT:

Background

In Kawasaki disease (KD), a vasculitis of unknown etiology, the most serious complication is the development of coronary artery aneurysm (CAA). To date, the exact pathomechanism of KD is unknown. Both environmental and genetic factors seem to be associated with the development of the disease.

Methods

Data on KD patients recruited from the population-based German Pediatric Surveillance Study during 2012-2014 were used to evaluate the impact of various factors from the perinatal and infancy period on the development of KD. The study design was a matched case-control study with respect to age, sex and place of residence (n = 308 KD cases, n = 326 controls). All KD patients were individually re-evaluated; all fulfilled the international diagnostic KD criteria. A stand

SUBMITTER: Meyer K 

PROVIDER: S-EPMC6390341 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature