Identification of recombination hotspots and quantitative trait loci for recombination rate in layer chickens.

ABSTRACT:

Background

The frequency of recombination events varies across the genome and between individuals, which may be related to some genomic features. The objective of this study was to assess the frequency of recombination events and to identify QTL (quantitative trait loci) for recombination rate in two purebred layer chicken lines.

Methods

A total of 1200 white-egg layers (WL) were genotyped with 580 K SNPs and 5108 brown-egg layers (BL) were genotyped with 42 K SNPs (single nucleotide polymorphisms). Recombination events were identified within half-sib families and both the number of recombination events and the recombination rate was calculated within each 0.5 Mb window of the genome. The 10% of windows with the highest recombination rate on each chromosome were considered t

SUBMITTER: Weng Z 

PROVIDER: S-EPMC6390344 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature