Resveratrol displays anti-inflammatory properties in an ex vivo model of immune mediated inflammatory arthritis.

ABSTRACT:

Background

Resveratrol is a natural polyphenol found in berries, roots and wine that is well known to have anti-inflammatory and anti-oxidative properties. The anti-inflammatory effect has been reported for both immune cells and connective tissues, but only few studies have investigated effects on immune mediated inflammatory arthritis. None of which have studied this effect when combining resveratrol with methotrexate or adalimumab, two major drugs in the treatment of immune mediated inflammatory arthritis.We therefore aimed to investigate the anti-inflammatory effect of resveratrol alone and in combination with methotrexate or adalimumab in ex vivo models of immune mediated inflammatory arthritis. We furthermore aimed to describe any variations in this effect based on disease act

SUBMITTER: Lomholt S 

PROVIDER: S-EPMC6390607 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature