Chest Compressions During Sustained Inflation During Cardiopulmonary Resuscitation in Newborn Infants Translating Evidence From Animal Studies to the Bedside.

ABSTRACT: Newborn infants receiving chest compressions in the delivery room have a high incidence of mortality (41%) and short-term neurological morbidity (e.g., 57% hypoxic-ischemic encephalopathy and seizures). Furthermore, infants who have no signs of life at 10 min despite chest compressions have 83% mortality, with 93% of survivors experiencing moderate-to-severe disability. The poor prognosis associated with receiving chest compressions in the delivery room raises questions as to whether improved cardiopulmonary resuscitation methods specifically tailored to the newborn could improve outcomes. Combining chest compressions during sustained inflation (CC+SI) has recently been shown to improve morbidity and mortality outcomes during cardiopulmonary resuscitation. Overall, CC+SI accomplishes the f

SUBMITTER: Schmolzer GM 

PROVIDER: S-EPMC6390679 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature