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Single-cell RNA-seq of cultured human adipose-derived mesenchymal stem cells.

ABSTRACT: Adipose-derived mesenchymal stem cells (ADSCs) show considerable promise for clinical applications in regenerative medicine. We performed a large-scale single-cell transcriptomic sequencing of 24,358 cultured human ADSCs from three donors. We provide a high-quality dataset, which would be a valuable resource for dissecting the intrapopulation heterogeneity of cultured ADSCs as well as interrogating lineage priming patterns for any interested lineages at single-cell resolution.

SUBMITTER: Liu X 

PROVIDER: S-EPMC6390702 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature

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Single-cell RNA-seq of cultured human adipose-derived mesenchymal stem cells.

Liu Xuanyu X   Xiang Qinqin Q   Xu Fen F   Huang Jiuzuo J   Yu Nanze N   Zhang Qixu Q   Long Xiao X   Zhou Zhou Z  

Scientific data 20190226

Adipose-derived mesenchymal stem cells (ADSCs) show considerable promise for clinical applications in regenerative medicine. We performed a large-scale single-cell transcriptomic sequencing of 24,358 cultured human ADSCs from three donors. We provide a high-quality dataset, which would be a valuable resource for dissecting the intrapopulation heterogeneity of cultured ADSCs as well as interrogating lineage priming patterns for any interested lineages at single-cell resolution. ...[more]

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