Blood Pressure Variability, Mortality, and Cardiovascular Outcomes in CKD Patients.

ABSTRACT:

Background and objectives

Short-term BP variability (derived from 24-hour ambulatory BP monitoring) and long-term BP variability (from clinic visit to clinic visit) are directly related to risk for cardiovascular events, but these relationships have been scarcely investigated in patients with CKD, and their prognostic value in this population is unknown.

Design, setting, participants, & measurements

In a cohort of 402 patients with CKD, we assessed associations of short- and long-term systolic BP variability with a composite end point of death or cardiovascular event. Variability was defined as the standard deviation of observed BP measurements. We further tested the prognostic value of these parameters for risk discrimination and reclassification.

Results

Mean ± SD s

SUBMITTER: Mallamaci F 

PROVIDER: S-EPMC6390905 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature