Prospective Biopsy-Based Study of CKD of Unknown Etiology in Sri Lanka.

ABSTRACT:

Background and objectives

A kidney disease of unknown cause is common in Sri Lanka's lowland (dry) region. Detailed clinical characterizations of patients with biopsy-proven disease are limited, and there is no current consensus on criteria for a noninvasive diagnosis.

Design, setting, participants, & measurements

We designed a prospective study in a major Sri Lankan hospital servicing endemic areas to ascertain pathologic and clinical characteristics of and assess risk factors for primary tubulointerstitial kidney disease. We used logistic regression to determine whether common clinical characteristics could be used to predict the presence of primary tubulointerstitial kidney disease on kidney biopsy.

Results

From 600 new patients presenting to a tertiary nephrology

SUBMITTER: Anand S 

PROVIDER: S-EPMC6390926 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature