Single recombinant and purified major allergens and peptides: How they are made and how they change allergy diagnosis and treatment.

ABSTRACT:

Objective

To review the current knowledge regarding recombinant and purified allergens and allergen-derived peptides.

Data sources

PubMed, homepages relevant to the topic, and the National Institutes of Health clinical trial database were searched.

Study selections

The literature was screened for studies describing purified and recombinant allergens and allergen-derived peptides. Studies relevant to the topic were included in this review.

Results

Advantages and drawbacks of pure and defined recombinant allergens and peptides over allergen extracts in the context of allergy research, diagnosis, and allergen immunotherapy are discussed. We describe how these molecules are manufactured, which products are currently available on the market, and what the regulative

SUBMITTER: Curin M 

PROVIDER: S-EPMC6390930 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature