Sensing the electrical activity of single ion channels with top-down silicon nanoribbons.

ABSTRACT: Using top-down fabricated silicon nanoribbons, we measure the opening and closing of ion channels alamethicin and gramicidin A. A capacitive model of the system is proposed to demonstrate that the geometric capacitance of the nanoribbon is charged by ion channel currents. The integration of top-down nanoribbons with electrophysiology holds promise for integration of electrically active living systems with artificial electronics.

SUBMITTER: Zhou W 

PROVIDER: S-EPMC6390970 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature