Functional Decline and Resilience in Older Women Receiving Adjuvant Chemotherapy for Breast Cancer.

ABSTRACT:

Objectives

To analyze self-reported changes in physical function in older women with breast cancer receiving adjuvant chemotherapy.

Design

Secondary analysis of the Cancer and Leukemia Group B (CALGB) 49907 prospective randomized clinical trial.

Setting

CALGB institutions in the United States.

Participants

Women aged 65 and older with Stage I to III breast cancer enrolled in CALGB 49907 who had physical function data from before and after receipt of adjuvant chemotherapy (N=256; mean age 71.5, range 65-85).

Measurements

Participants were administered the physical function subscale of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire before chemotherapy, at the end of chemotherapy, and 12 months after chemotherap

SUBMITTER: Hurria A 

PROVIDER: S-EPMC6391210 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature