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Achievement of Guideline-Recommended Weight Loss Among Patients With Ischemic Stroke and Obesity.


ABSTRACT: Background and Purpose- The proportion of patients with acute ischemic stroke or transient ischemic attack (TIA) and obesity who successfully achieve goals for weight reduction recommended by major professional organizations is unknown. Methods- We examined the experience of participants in the placebo group of the IRIS trial (Insulin Resistance Intervention after Stroke) with a body mass index ≥30 kg/m2 at entry. Patients were of age ≥40 years, with a qualifying stroke or TIA within 180 days of randomization and documented insulin resistance without diabetes mellitus. Weights at baseline and at years 1 and 2 after entry were analyzed to determine the proportion of patients achieving a 5% weight loss and achievement of body mass index <27 kg/m2. Results- Of 1937 subje

SUBMITTER: Dearborn JL 

PROVIDER: S-EPMC6391736 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature