Childhood trauma moderates inhibitory control and anterior cingulate cortex activation during stress.

ABSTRACT:

Objective

The anterior cingulate cortex (ACC) is critical for both stress and inhibitory control processes and has been implicated in childhood trauma. This prospective study tested the hypothesis that early trauma moderates the association between inhibitory control during late childhood and ACC stress reactivity during adolescence.

Method

Sixty-four adolescents were stratified into higher- or lower-childhood-trauma groups. Inhibitory control was indicated by fewer errors on a Stroop Color-Word task. Personalized stress cues during functional magnetic resonance imaging assessed neural correlates of stress in adolescents.

Results

Using a priori-defined anterior (rCZa) and posterior rostral cingulate zones of the ACC, associated with Stroop Color-Word task performance

SUBMITTER: Zhai ZW 

PROVIDER: S-EPMC6392043 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature