Prognostic Hemostasis Biomarkers in Acute Ischemic Stroke.

ABSTRACT: Objectives- The prediction of patients at risk for poor clinical outcome after acute ischemic stroke remains challenging. An imbalance of coagulation factors may play an important role in progression and prognosis of these patients. In this systematic review, we assessed the current literature on hemostasis biomarkers and the association with poor clinical outcome in acute ischemic stroke. Approach and Results- A systematic search of Embase, Medline, Cochrane Library, Web of Science, and Google Scholar was performed on studies reporting on hemostasis biomarkers and clinical outcome after acute ischemic stroke. Studies were considered eligible if blood samples were collected within 72 hours after symptom onset. Additionally, clinical outcome should be assessed using a disability score (Bart

SUBMITTER: Donkel SJ 

PROVIDER: S-EPMC6392207 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature