Global burden of maternal and congenital syphilis and associated adverse birth outcomes-Estimates for 2016 and progress since 2012.

ABSTRACT:

Background

In 2007 the World Health Organization (WHO) launched the global initiative to eliminate mother-to-child transmission of syphilis (congenital syphilis, or CS). To assess progress towards the goal of <50 CS cases per 100,000 live births, we generated regional and global estimates of maternal and congenital syphilis for 2016 and updated the 2012 estimates.

Methods

Maternal syphilis estimates were generated using the Spectrum-STI model, fitted to sentinel surveys and routine testing of pregnant women during antenatal care (ANC) and other representative population data. Global and regional estimates of CS used the same approach as previous WHO estimates.

Results

The estimated global maternal syphilis prevalence in 2016 was 0.69% (95% confidence interval: 0.57-0.

SUBMITTER: Korenromp EL 

PROVIDER: S-EPMC6392238 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature