Abdominal obesity, sarcopenia, and osteoporosis are associated with frailty in men living with and without HIV.

ABSTRACT:

Objective

The relationships between frailty and body composition in older adults with HIV infection are poorly understood. We sought to describe associations between frailty and measures of body composition among adult men with HIV and without HIV.

Design/methods

Men with and without HIV (age 50-69 years) in the Multicenter AIDS Cohort Study (MACS) Bone Strength Substudy were included if evaluated for frailty (by Fried phenotype) and body composition [BMI, waist circumference, abdominal visceral (VAT) and subcutaneous (SAT) adipose tissue, sarcopenia, and osteopenia/osteoporosis]. All participants with HIV infection were on antiretroviral therapy. Multivariate multinomial logistic regression models were used to determine associations of frailty with body composition.

Resu

SUBMITTER: Hawkins KL 

PROVIDER: S-EPMC6392465 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature