Weight loss increases all-cause mortality in overweight or obese patients with diabetes: A meta-analysis.

ABSTRACT:

Background

Overweight and obese patients with diabetes are advised to lose weight to improve their health; however, recent studies have demonstrated that weight loss may be associated with worse long-term survival in patients with diabetes. This meta-analysis aimed to examine the relationships between weight loss and all-cause mortality in overweight or obese individuals with diabetes.

Methods

We searched the PubMed and EMBASE databases from inception to February 2017. We included prospective studies that reported sufficient information to extract mortality-specific relative risks (RRs) with corresponding 95% confidence intervals (CIs). RRs with 95% CIs were pooled using a random-effects model. A subgroup analysis was also performed to explore sources of heterogeneity.

Re

SUBMITTER: Chen Y 

PROVIDER: S-EPMC6392938 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature