Sentinel lymph node biopsy in microinvasive ductal carcinoma in situ.

ABSTRACT:

Background

Microinvasive breast cancer is an uncommon pathological entity. Owing to the rarity of this condition, its surgical axillary management and overall prognosis remain controversial.

Methods

A database was analysed to identify patients with microinvasive ductal carcinoma in situ (DCIS) who had surgery for invasive breast cancer at the European Institute of Oncology, Milan, between 1998 and 2010. Women who had undergone axillary staging by sentinel lymph node biopsy were included in the study.

Results

Of 257 women with microinvasive breast cancer who underwent sentinel lymph node biopsy (SLNB), 226 (87·9 per cent) had negative sentinel lymph nodes (SLNs) and 31 had metastatic SLNs. Twelve patients had isolated tumour cells (ITCs), 14 had micrometastases and fiv

SUBMITTER: Magnoni F 

PROVIDER: S-EPMC6393177 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature