Seed culture pre-adaptation of Bacillus coagulans MA-13 improves lactic acid production in simultaneous saccharification and fermentation.

ABSTRACT:

Background

Lignocellulosic biomass is an abundant and sustainable feedstock, which represents a promising raw material for the production of lactic acid via microbial fermentation. However, toxic compounds that affect microbial growth and metabolism are released from the biomass upon thermochemical pre-treatment. So far, susceptibility of bacterial strains to biomass-derived inhibitors still represents a major barrier to lactic acid production from lignocellulose. Detoxification of the pre-treated lignocellulosic material by water washing is commonly performed to alleviate growth inhibition of the production microorganism and achieve higher production rates.

Results

In this study, we assessed the feasibility of replacing the washing step with integrated cellular adaptation d

SUBMITTER: Aulitto M 

PROVIDER: S-EPMC6394018 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature