Exacerbations of Chronic Obstructive Pulmonary Disease Tool to assess the efficacy of acute treatment.

ABSTRACT:

Background and objective

The Exacerbations of Chronic Obstructive Pulmonary Disease Tool-Patient-Reported Outcomes (EXACT-PRO) has been suggested as a reliable and valid measure for early assessment of COPD exacerbations and perceived recovery. However, there has been no evidence for EXACT-PRO efficacy in assessing recovery from treatment in a randomized controlled trial. The study evaluated the reliability, validity, and responsiveness of EXACT-PRO for the evaluation of the efficacy of acute treatment in patients with COPD exacerbation.

Methods

In a Phase III randomized controlled study for assessing the efficacy of antibiotic treatment on COPD exacerbation, EXACT-PRO was evaluated in the responders and non-responders.

Results

A total of 295 patients were analyzed (2

SUBMITTER: Choi HS 

PROVIDER: S-EPMC6394236 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature