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Exclusive enteral nutrition versus corticosteroids for treatment of pediatric Crohn's disease: a meta-analysis.


ABSTRACT:

Background

Many studies have examined the effects of exclusive enteral nutrition (EEN) in children with Crohn's disease (CD), but corticosteroids are considered a superior therapy and are frequently used in China. This meta-analysis aims to compare the efficacy of EEN with corticosteroids in treating pediatric CD.

Methods

A comprehensive retrieval from medical databases, including PubMed, EMBASE, MEDLINE, Web of Science, Wanfang data, VIP and CNKI, was performed using the search terms "diet therapy", "exclusive enteral nutrition", "Crohn's disease", "inflammatory bowel diseases", "child" and "pediatrics" from January 1990 to April 2017.

Results

We included 18 studies from 1329 identified sources in this meta-analysis. EEN was as effective as corticosteroids in inducin

SUBMITTER: Yu Y 

PROVIDER: S-EPMC6394648 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature