Impact of pre-operative antimicrobial treatment on microbiological findings from endocardial specimens in infective endocarditis.

ABSTRACT: Treatment of infective endocarditis (IE) should be initiated promptly. This might hamper the chances to identify the causative organism in blood cultures. Microbiological sampling of infected valve in patients undergoing surgery might identify the causative organism. The impact of pre-operative antimicrobial treatment on the yield of valve samples is not known. This study evaluated the impact of the duration of the pre-operative antibiotic treatment on valve culture and 16S rRNA PCR findings from resected endocardial samples. Patients meeting the modified Duke criteria of definite or possible IE and undergoing valve surgery due to IE during 2011-2016 were included from Southern Finland. Eighty-seven patients were included. In patients with shorter than 2 weeks of pre-operative antimicrobia

SUBMITTER: Halavaara M 

PROVIDER: S-EPMC6394703 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature