Patterned frequency-modulated oral stimulation in preterm infants: A multicenter randomized controlled trial.

ABSTRACT:

Objective

To evaluate the effect of patterned, frequency-modulated oro-somatosensory stimulation on time to full oral feeds in preterm infants born 26-30 weeks gestation.

Study design

This is a multicenter randomized controlled trial. The experimental group (n = 109) received patterned, frequency-modulated oral stimulation via the NTrainer system through a pulsatile pacifier and the control group (n = 101) received a non-pulsatile pacifier. Intent-to-treat analysis (n = 210) was performed to compare the experimental and control groups and the outcomes were analyzed using generalized estimating equations. Time-to-event analyses for time to reach full oral feeds and length of hospital stay were conducted using Cox proportional hazards models.

Results

The experimental gr

SUBMITTER: Song D 

PROVIDER: S-EPMC6394921 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature