Genetic and environmental influences on gambling disorder liability: a replication and combined analysis of two twin studies.

ABSTRACT:

Background

Gambling disorder (GD), recognized in Diagnostic and Statistical Manual of Mental Disorders, Version 5 (DSM-5) as a behavioral addiction, is associated with a range of adverse outcomes. However, there has been little research on the genetic and environmental influences on the development of this disorder. This study reports results from the largest twin study of GD conducted to date.

Methods

Replication and combined analyses were based on samples of 3292 (mean age 31.8, born 1972-79) and 4764 (mean age 37.7, born 1964-71) male, female, and unlike-sex twin pairs from the Australian Twin Registry. Univariate biometric twin models estimated the proportion of variation in the latent GD liability that could be attributed to genetic, shared environmental, and unique env

SUBMITTER: Davis CN 

PROVIDER: S-EPMC6395556 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature