Ontology highlight
ABSTRACT:
SUBMITTER: Islam A
PROVIDER: S-EPMC6395645 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Islam Ashekul A Emran Talha Bin TB Yamamoto Daisuke S DS Iyori Mitsuhiro M Amelia Fitri F Yusuf Yenni Y Yamaguchi Ririka R Alam Md Shah MS Silveira Henrique H Yoshida Shigeto S
Scientific reports 20190228 1
The saliva of hematophagous arthropods is enriched with a complex mixture of antihemostatic molecules, the biological functions of which are largely unknown. Anopheline antiplatelet protein (AAPP) from malaria vector mosquito exhibits strong antiplatelet activity when bound directly to host collagen by its C-terminus and through its N-terminus with Ca<sup>2+</sup>-binding activity. To investigate the biological functions of AAPP in blood feeding behavior and malaria transmission, we generated tr ...[more]