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First bloodstream infection due to Prototheca zopfii var. hydrocarbonea in an immunocompromised patient.

ABSTRACT: Here we describe a bloodstream infection due to P. zopfii var. hydrocarbonea in a patient with acute lymphoblastic leukemia. Identification was performed by DNA sequencing of the D1/D2 domain of 26s ribosomal DNA and by MALDI-TOF MS technique. Antifungal susceptibility tests against amphotericin B, fluconazole, itraconazole, and voriconazole showed the following MIC values, respectively: 0.25 mg/L, 128 mg/L, 0.064 mg/L, and 0.125 mg/L. The patient received amphotericin B treatment with a successful outcome.

SUBMITTER: Fernandez NB 

PROVIDER: S-EPMC6395827 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature

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First bloodstream infection due to <i>Prototheca zopfii</i> var. <i>hydrocarbonea</i> in an immunocompromised patient.

Fernández Norma B NB   Taverna Constanza G CG   Vivot Matías M   Córdoba Susana S   Paravano Lucia L  

Medical mycology case reports 20190216

Here we describe a bloodstream infection due to <i>P. zopfii</i> var<i>. hydrocarbonea</i> in a patient with acute lymphoblastic leukemia. Identification was performed by DNA sequencing of the D1/D2 domain of 26s ribosomal DNA and by MALDI-TOF MS technique. Antifungal susceptibility tests against amphotericin B, fluconazole, itraconazole, and voriconazole showed the following MIC values, respectively: 0.25 mg/L, 128 mg/L, 0.064 mg/L, and 0.125 mg/L. The patient received amphotericin B treatment  ...[more]

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