In Situ Generation of Chiroptically-Active Gold-Peptide Superstructures Promoted by Iodination.

ABSTRACT: Peptide-mediated routes to the synthesis of plasmonic nanoparticles have been drawing increasing attention for the development of chiroptically active nanoscale architectures. However, designing a multifunctional peptide able to drive the formation of structurally defined nanomaterials endowed with specific functionalities is still challenging. In this work, iodination has been devised as a strategy to strengthen Au-reduction capability of the amyloidogenic peptide DFNKF and combine it with its distinctive self-assembly features. Thanks to the Au-mediated C-I activation on the phenylalanine iodobenzenes, the peptides yield efficient Au-reduction ability promoting the synthesis of Au nanoparticles, and simultaneously working as templates for their spontaneous self-assembly into spherical su

SUBMITTER: Pigliacelli C 

PROVIDER: S-EPMC6396319 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature