Determinants of survival of people living with HIV/AIDS on antiretroviral therapy in Brazil 2006-2015.

ABSTRACT:

Background

We compared AIDS-related mortality rates in people living with HIV (PLHIV) starting antiretroviral therapy (ART) in Brazil during 2006-2015 and examined associated risk factors .

Methods

Data on ART use in PLHIV and AIDS mortality in Brazil was analysed with piecewise constant exponential models. Mortality rates and hazard ratios were estimated for 0-6, 6-12, 13-24, 25-36 and > 36 months of ART use and adjusted for region, age, sex, baseline CD4 cell count and calendar year of ART initiation. An additional analysis restricted to those with data on risk group was also performed.

Results

269,076 individuals were included in the analysis, 165,643 (62%) males and 103,433 (38%) females, with 1,783,305 person-years of follow-up time. 21,749 AIDS deaths were repor

SUBMITTER: Mangal TD 

PROVIDER: S-EPMC6396460 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature