The composition of the pulmonary microbiota in sarcoidosis - an observational study.

ABSTRACT:

Background

Sarcoidosis is a systemic disease of unknown etiology. The disease mechanisms are largely speculative and may include the role microbial patterns that initiate and drive an underlying immune process. The aim of this study was to characterize the microbiota of the lung of patients with sarcoidosis and compare its composition and diversity with the results from patients with other interstitial lung disease (ILD) and historic healthy controls.

Methods

Patients (sarcoidosis, n = 31; interstitial lung disease, n = 19) were recruited within the PULMOHOM study, a prospective cohort study to characterize inflammatory processes in pulmonary diseases. Bronchoscopy of the middle lobe or the lingula was performed and the recovered fluid was immediately sent for analysis of th

SUBMITTER: Becker A 

PROVIDER: S-EPMC6396534 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature