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Two decades of embryonic stem cells: a historical overview.


ABSTRACT:

SUBMITTER: Eguizabal C 

PROVIDER: S-EPMC6396646 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Two decades of embryonic stem cells: a historical overview.

Eguizabal C C   Aran B B   Chuva de Sousa Lopes S M SM   Geens M M   Heindryckx B B   Panula S S   Popovic M M   Vassena R R   Veiga A A  

Human reproduction open 20190129 1


<h4>Study question</h4>How did the field of stem cell research develop in the years following the derivation of the first human embryonic stem cell (hESC) line?<h4>Summary answer</h4>Supported by the increasing number of clinical trials to date, significant technological advances in the past two decades have brought us ever closer to clinical therapies derived from pluripotent cells.<h4>What is known already</h4>Since their discovery 20 years ago, the use of human pluripotent stem cells has prog  ...[more]

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