A causal role for the precuneus in network-wide theta and gamma oscillatory activity during complex memory retrieval.

ABSTRACT: Complex memory of personal events is thought to depend on coordinated reinstatement of cortical representations by the medial temporal lobes (MTL). MTL-cortical theta and gamma coupling is believed to mediate such coordination, but which cortical structures are critical for retrieval and how they influence oscillatory coupling is unclear. We used magnetoencephalography (MEG) combined with continuous theta burst stimulation (cTBS) to (i) clarify the roles of theta and gamma oscillations in network-wide communication during naturalistic memory retrieval, and (ii) understand the causal relationship between cortical network nodes and oscillatory communication. Retrieval was associated with MTL-posterior neocortical theta phase coupling and theta-gamma phase-amplitude coupling relative to a res

SUBMITTER: Hebscher M 

PROVIDER: S-EPMC6397002 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature