Prognostic Value of Preoperative Systemic Immune-Inflammation Index in Patients with Cervical Cancer.

ABSTRACT: The systemic immune-inflammation index (SII) based on peripheral lymphocyte, neutrophil and platelet counts has been considered a good index that reflects the local immune response and systemic inflammation. However, the use of the SII has not been reported in cervical cancer. In this study, Kaplan-Meier survival analysis showed that a high SII was associated with poor prognosis in cervical cancer patients in the primary and validation cohorts. A higher SII had a significant correlation with larger tumours but had no correlation with other clinicopathological parameters. Among all systemic immune indexes, the SII is the only independent prognostic factor for cervical cancer patients. Compared with the area under the curve for the neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio

SUBMITTER: Huang H 

PROVIDER: S-EPMC6397230 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature