Evaluation of iron stores in hemodialysis patients on maintenance ferric Carboxymaltose dosing.

ABSTRACT: BACKGROUND:Iron is administered intravenously (IV) to many dialysis patients at regular intervals and iron stores are evaluated through periodic measurements of ferritin and transferrin saturation (TSAT). In patients without kidney diseases, large single doses of IV iron lead to a transient rise in serum ferritin that does not reflect iron stores. It is not known whether and to what extent smaller IV iron doses used to maintain adequate stores in hemodialysis patients lead to transient spurious elevations of ferritin and TSAT. METHODS:Ferritin and TSAT were serially determined over four weeks after the administration of ferric carboxymaltose (FCM) in hemodialysis patients on a stable maintenance FCM dosing regimen of 100 mg or 200 mg every four weeks. RESULTS:Ferritin values increased by 1

SUBMITTER: Diebold M 

PROVIDER: S-EPMC6397449 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature