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Nonlinear dynamics underlying sensory processing dysfunction in schizophrenia.


ABSTRACT: Natural systems, including the brain, often seem chaotic, since they are typically driven by complex nonlinear dynamical processes. Disruption in the fluid coordination of multiple brain regions contributes to impairments in information processing and the constellation of symptoms observed in neuropsychiatric disorders. Schizophrenia (SZ), one of the most debilitating mental illnesses, is thought to arise, in part, from such a network dysfunction, leading to impaired auditory information processing as well as cognitive and psychosocial deficits. Current approaches to neurophysiologic biomarker analyses predominantly rely on linear methods and may, therefore, fail to capture the wealth of information contained in whole EEG signals, including nonlinear dynamics. In this study, delay differen

SUBMITTER: Lainscsek C 

PROVIDER: S-EPMC6397565 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature