Development of Electrochemical Nanosensor for the Detection of Malaria Parasite in Clinical Samples.

ABSTRACT: In this study, electrochemical nanosensors were developed from the synthesized metal oxide (MO) nanoparticles by supporting it on a gold electrode (Au). The activity of the developed nanosensor toward the detection of malaria biomarker (β-hematin) was determined and the optimum conditions at which the maximum detection and quantification occurred were established. β-Hematin current response at the sensors was higher when compared with the bare Au electrode and followed the order Au-CuO (C) > Au-CuO (M) > Au-Fe₂O3 (M) > Au-Fe₂O3 (C) > Au-Al₂O3 (M) > Au-Al₂O3 (C) > bare Au. The developed sensors were stable with a relatively low current drop (10.61-17.35 %) in the analyte. Au-CuO sensor had the best performance toward the biomarker and quantitative

SUBMITTER: Obisesan OR 

PROVIDER: S-EPMC6397833 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature