Characteristics and long-term outcomes of advanced pleural mesothelioma in Latin America (MeSO-CLICaP).

ABSTRACT:

Background

Malignant pleural mesothelioma (MPM) is an aggressive tumor, associated with poor prognosis. There is a lack of information about the clinical and pathological features related with survival in the Latin American population.

Methods

The MeSO-CLICaP registry identified 302 patients with advanced MPM diagnosed and treated between January 2008 and March 2016. The Cox model was applied to determine the variables associated with survival. A random forest tree model was built to predict the response to first-line chemotherapy among Latin American patients.

Results

The median age was 61.1 years (SD 10.6 years), 191 (63.2%) were men, 65.9% were ever smokers, and 38.7% had previous exposure to asbestos. A total of 237 (78.5%) had epithelioid tumors, and 188 (62.3%)

SUBMITTER: Rojas L 

PROVIDER: S-EPMC6397921 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature