Resting heart rate and risk of type 2 diabetes: A prospective cohort study and meta-analysis.

ABSTRACT:

Background

Positive association between resting heart rate (RHR) and risk of type 2 diabetes (T2D) has been documented in several studies. However, whether RHR is an independent predictor of T2D and its potential interaction with other risk factors of T2D remain unclear.

Methods

We conducted a prospective cohort study of 31 156 men from the Health Professionals Follow-up Study (1992-2012). Cox proportional hazard model was used to examine the association between RHR and T2D risk. We further examined whether this association is modified by known risk factors. Lastly, we conducted a meta-analysis of prospective cohort studies.

Results

During 505 380 person-years of follow-up, we identified 2338 incident T2D cases. The multivariable-adjusted hazard ratio (HR) comparing t

SUBMITTER: Lee DH 

PROVIDER: S-EPMC6398339 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature