Gcn5 histone acetyltransferase is present in the mitoplasts.
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ABSTRACT:
SUBMITTER: Montanari A
PROVIDER: S-EPMC6398455 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
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Gcn5 histone acetyltransferase is present in the mitoplasts.
Montanari Arianna A Leo Manuela M De Luca Veronica V Filetici Patrizia P Francisci Silvia S
Biology open 20190218 2
In <i>Saccharomyces cerevisiae</i> the Lysine-acetyltransferase Gcn5 (KAT2) is part of the SAGA complex and is responsible for histone acetylation widely or at specific lysines. In this paper we report that <i>G</i> <i>CN5</i> deletion differently affects the growth of two strains. The defective mitochondrial phenotype is related to a marked decrease in mtDNA content, which also involves the deletion of specific regions of the molecule. We also show that in wild-type mitochondria the Gcn5 protei ...[more]
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