Surgical fasciectomy versus collagenase injection in treating recurrent Dupuytren disease: study protocol of a randomised controlled trial.

ABSTRACT:

Introduction

There is no definitive cure for Dupuytren disease (DD), and recurrence of finger contractures after treatment is common. Surgical fasciectomy is considered the standard treatment method for recurrence, although associated with a high incidence of complications. Collagenase injection, a non-surgical treatment option, has been shown to be a safe and effective method; however, most studies regarding collagenase have involved first-time treatment. Collagenase efficacy in patients with recurrent DD beyond the immediate effect has not yet been determined. The aim of our study is to compare surgical fasciectomy and collagenase injection in treating recurrent DD.

Methods and analysis

The study is a single-centre randomised controlled trial. Inclusion criteria are recurr

SUBMITTER: Nordenskjold J 

PROVIDER: S-EPMC6398619 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature