Microsimulation model for the health economic evaluation of osteoporosis interventions: study protocol.

ABSTRACT:

Introduction

Osteoporosis is a systemic skeletal disease that is characterised by reduced bone strength and increased fracture risk. Osteoporosis-related fractures impose enormous disease and economic burden to the society. Although many treatments and health interventions are proven effective to prevent fractures, health economic evaluation adds evidence to their economic merits. Computer simulation modelling is a useful approach to extrapolate clinical and economic outcomes from clinical trials and it is increasingly used in health economic evaluation. Many osteoporosis health economic models have been developed in the past decades; however, they are limited to academic use and there are no publicly accessible health economic models of osteoporosis.

Methods and analysis

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SUBMITTER: Si L 

PROVIDER: S-EPMC6398703 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature